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Results (1,548 reactions)

RHEA:23128 4-hydroxybutanoate + ATP + CoA = 4-hydroxybutanoyl-CoA + AMP + diphosphate
  • EC:6.2.1.40 4-hydroxybutyrate--CoA ligase (AMP-forming)
2 protein(s) (UniProtKB)
RHEA:23148 propanoate + ATP = propanoyl phosphate + ADP 1,626 protein(s) (UniProtKB)
RHEA:23260 (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD+ = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADH + H+ 2,057 protein(s) (UniProtKB)
RHEA:23264 (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADP+ = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADPH + H+
RHEA:23276 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde
RHEA:23456 (9Z,12Z)-octadecadienoate + AH2 + O2 = crepenynate + A + 2 H2O
RHEA:23520 propanoate + acetyl-CoA = propanoyl-CoA + acetate 2 protein(s) (UniProtKB)
RHEA:23580 prostaglandin H2 = prostaglandin I2 845 protein(s) (UniProtKB)
RHEA:23600 L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate
RHEA:23728 (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 = prostaglandin H2 + A + H2O 567 protein(s) (UniProtKB)
RHEA:23800 L-methionine + H2O = methanethiol + 2-oxobutanoate + NH4+ 2,378 protein(s) (UniProtKB)
RHEA:23948 4-hydroxybutanoate + NAD+ = succinate semialdehyde + NADH + H+ 3 protein(s) (UniProtKB)
RHEA:23960 hexadecanoate + 2 H2O2 + H+ = pentadecanal + CO2 + 3 H2O
RHEA:24072 (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate = 12,13-epoxy-(9Z,11E,15Z)-octadecatrienoate + H2O
RHEA:24156 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP
RHEA:24216 (2E,6E)-farnesal + NAD+ + H2O = (2E,6E)-farnesoate + NADH + 2 H+ 1,833 protein(s) (UniProtKB)
RHEA:24404 (3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA 9,433 protein(s) (UniProtKB)
RHEA:24508 prostaglandin F2α + NADP+ = prostaglandin E2 + NADPH + H+ 328 protein(s) (UniProtKB)
RHEA:24734 4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde 4,580 protein(s) (UniProtKB)
RHEA:24789 (2E,4Z)-2-hydroxy-6-oxononadienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + succinate + H+
RHEA:24809 (2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O 41,108 protein(s) (UniProtKB)
RHEA:24813 L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate 61,806 protein(s) (UniProtKB)
RHEA:24923 L-homoserine = 2-oxobutanoate + NH4+ 1,329 protein(s) (UniProtKB)
RHEA:25046 (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H+
RHEA:25074 (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate = (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate + H2O 10 protein(s) (UniProtKB)
RHEA:25168 6-hydroxyhexan-6-olide = 6-oxohexanoate + H+
RHEA:25395 (9Z,12Z)-octadecadienoate + O2 = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate 599 protein(s) (UniProtKB)
RHEA:25399 (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate
  • EC:5.4.4.6 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase
2 protein(s) (UniProtKB)
RHEA:25404 (S)-2-ethyl-2-hydroxy-3-oxobutanoate = (R)-3-hydroxy-3-methyl-2-oxopentanoate
RHEA:25480 acetoacetate + succinyl-CoA = acetoacetyl-CoA + succinate 4 protein(s) (UniProtKB)
RHEA:25767 3-carboxy-2-oxobutanoate + H+ = 2-oxobutanoate + CO2
RHEA:26132 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H+
2,275 protein(s) (UniProtKB)
RHEA:26136 N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + H2O = ethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate 416 protein(s) (UniProtKB)
RHEA:26381 4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+ 5 protein(s) (UniProtKB)
RHEA:26470 16-hydroxyhexadecanoate + (E)-feruloyl-CoA = 16-feruloyloxyhexadecanoate + CoA
  • EC:2.3.1.188 omega-hydroxypalmitate O-feruloyl transferase
1 protein(s) (UniProtKB)
RHEA:26506 (9Z)-octadecenamide + H2O = (9Z)-octadecenoate + NH4+ 414 protein(s) (UniProtKB)
RHEA:26514 cyclohexan-1,2-dione + H2O = 6-oxohexanoate + H+ 1 protein(s) (UniProtKB)
RHEA:27654 2-oxobutanoate + pyruvate + H+ = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + CO2 2 protein(s) (UniProtKB)
RHEA:27806 acetoacetate + acetyl-CoA = acetoacetyl-CoA + acetate
6 protein(s) (UniProtKB)
RHEA:27870 (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + anthranilate + H+
  • EC:3.7.1.13 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase
1 protein(s) (UniProtKB)
RHEA:27918 propanal + NADP+ + H2O = propanoate + NADPH + 2 H+
4 protein(s) (UniProtKB)
RHEA:28010 propanoyl-CoA + succinate = propanoate + succinyl-CoA 2 protein(s) (UniProtKB)
RHEA:28022 octanoate + holo-[ACP] + ATP = octanoyl-[ACP] + AMP + diphosphate
2 protein(s) (UniProtKB)
RHEA:28054 2-oxobutanoate + CoA = propanoyl-CoA + formate
1 protein(s) (UniProtKB)
RHEA:28174 (9S)-hydroperoxy-(10E,12Z)-octadecadienoate = colneleate + H2O 4 protein(s) (UniProtKB)
RHEA:28178 (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate = colnelenate + H2O
RHEA:28214 prostaglandin H2 + [thioredoxin]-dithiol = prostaglandin F2α + [thioredoxin]-disulfide 349 protein(s) (UniProtKB)
RHEA:29751 acetoacetate(in) = acetoacetate(out)
RHEA:29755 (R)-lipoate(in) = (R)-lipoate(out)
RHEA:29759 octanoate(in) = octanoate(out)
RHEA:29843 propanoate + ATP + CoA = propanoyl-CoA + ADP + phosphate
RHEA:30071 butanoate + acetyl-CoA = butanoyl-CoA + acetate
1,221 protein(s) (UniProtKB)
RHEA:30115 decanoyl-[ACP] + H2O = decanoate + holo-[ACP] + H+
1 protein(s) (UniProtKB)
RHEA:30119 dodecanoyl-[ACP] + H2O = dodecanoate + holo-[ACP] + H+
  • EC:3.1.2.21 dodecanoyl-[acyl-carrier-protein] hydrolase
2 protein(s) (UniProtKB)
RHEA:30123 tetradecanoyl-[ACP] + H2O = tetradecanoate + holo-[ACP] + H+ 2,836 protein(s) (UniProtKB)
RHEA:30131 octanoyl-[ACP] + H2O = octanoate + holo-[ACP] + H+
1 protein(s) (UniProtKB)
RHEA:30135 dodecanoyl-CoA + H2O = dodecanoate + CoA + H+
10,486 protein(s) (UniProtKB)
RHEA:30139 octadecanoyl-CoA + H2O = octadecanoate + CoA + H+
31 protein(s) (UniProtKB)
RHEA:30143 octanoyl-CoA + H2O = octanoate + CoA + H+
10,463 protein(s) (UniProtKB)
RHEA:30291 (9Z,12Z)-octadecadienoate + O2 = (9S)-hydroperoxy-(10E,12Z)-octadecadienoate 31 protein(s) (UniProtKB)
RHEA:30751 hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
9,135 protein(s) (UniProtKB)
RHEA:30763 L-valine + NAD+ + H2O = 3-methyl-2-oxobutanoate + NH4+ + NADH + H+ 1,203 protein(s) (UniProtKB)
RHEA:30879 prop-2-ynal + NAD+ + H2O = propynoate + NADH + 2 H+
RHEA:30915 a β-D-glucosyl-(1↔1ʼ)-N-acylsphing-4-enine + H2O = β-D-glucosyl-(1↔1)-sphing-4-enine + a fatty acid 1 protein(s) (UniProtKB)
RHEA:31151 L-selenocystathionine + H2O = L-selenocysteine + 2-oxobutanoate + NH4+
1,328 protein(s) (UniProtKB)
RHEA:31251 (S)-3-hydroxyisobutanoyl-CoA + H2O = (S)-3-hydroxy-2-methylpropanoate + CoA + H+
RHEA:31267 6-hydroxyhexanoate + NADP+ = 6-oxohexanoate + NADPH + H+
RHEA:31275 (S)-3-hydroxy-2-methylpropanoate + NAD+ = (S)-2-methyl-3-oxopropanoate + NADH + H+
RHEA:31295 (2E)-2-hydroxypenta-2,4-dienoate = 2-oxopent-4-enoate
RHEA:31555 (5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate
  • EC:2.3.1.247 (5S)-5-amino-3-oxohexanoate:acetyl-CoA ethylamine transferase
3 protein(s) (UniProtKB)
RHEA:31579 (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (5S,8R,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate
  • EC:5.4.4.5 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase
4 protein(s) (UniProtKB)
RHEA:31687 (9Z,12Z,15Z)-octadecatrienoate + O2 = (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate 1 protein(s) (UniProtKB)
RHEA:31691 (9Z,12Z)-octadecadienoate + O2 = (9R)-hydroperoxy-(10E,12Z)-octadecadienoate
RHEA:31695 (9Z,12Z)-octadecadienoate + O2 = (8E,10R,12Z)-10-hydroperoxyoctadeca-8,12-dienoate 3 protein(s) (UniProtKB)
RHEA:31771 an all-trans-retinyl ester + H2O = 11-cis-retinol + a fatty acid + H+ 1,086 protein(s) (UniProtKB)
RHEA:31775 all-trans-retinyl hexadecanoate + H2O = 11-cis-retinol + hexadecanoate + H+ 1,086 protein(s) (UniProtKB)
RHEA:31779 an all-trans-retinyl ester + H2O = 13-cis-retinol + a fatty acid + H+
  • EC:3.1.1.90 all-trans-retinyl ester 13-cis isomerohydrolase
2 protein(s) (UniProtKB)
RHEA:32135 2-oxobutanoate + 2 oxidized [2Fe-2S]-[ferredoxin] + CoA = propanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + H+
RHEA:32307 (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O 4 protein(s) (UniProtKB)
RHEA:32507 4-isopropenyl-7-methyloxepan-2-one + H2O = 6-hydroxy-3-isopropenylheptanoate + H+ 1 protein(s) (UniProtKB)
RHEA:32511 (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O = (3R,6R)-6-hydroxy-3-isopropenylheptanoate + H+
RHEA:32515 (4S,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O = (3S,6R)-6-hydroxy-3-isopropenylheptanoate + H+
RHEA:32535 (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate 1 protein(s) (UniProtKB)
RHEA:32591 (4R,7S)-7-isopropyl-4-methyloxepan-2-one + H2O = (3R,6S)-6-hydroxy-3,7-dimethyloctanoate + H+
RHEA:32595 7-isopropyl-4-methyloxepan-2-one + H2O = 6-hydroxy-3,7-dimethyloctanoate + H+ 1 protein(s) (UniProtKB)
RHEA:32715 (2R,3S)-3-methylmalate + NAD+ = 2-oxobutanoate + CO2 + NADH 1 protein(s) (UniProtKB)
RHEA:32731 a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H+ 5,258 protein(s) (UniProtKB)
RHEA:32875 a 1-acyl-sn-glycerol + H2O = glycerol + a fatty acid + H+
RHEA:32935 a cardiolipin + H2O = 1ʼ-[1,2-diacyl-sn-glycero-3-phospho],3ʼ-[1-acyl-sn-glycero-3-phospho]-glycerol + a fatty acid + H+
2 protein(s) (UniProtKB)
RHEA:32967 a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O = sn-glycero-3-phosphoethanolamine + a fatty acid + H+
1 protein(s) (UniProtKB)
RHEA:32979 a 1-acyl-sn-glycero-3-phospho-L-serine + H2O = sn-glycero-3-phospho-L-serine + a fatty acid + H+ 336 protein(s) (UniProtKB)
RHEA:32987 a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + a fatty acid + H+
1 protein(s) (UniProtKB)
RHEA:33223 2-oxobutanoate + NAD+ + CoA = propanoyl-CoA + CO2 + NADH
RHEA:33271 a triacyl-sn-glycerol + H2O = a 1,2-diacyl-sn-glycerol + a fatty acid + H+
RHEA:33275 a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H+ 8,596 protein(s) (UniProtKB)
RHEA:33283 2-hydroxycyclohexan-1-one + NADPH + O2 = 6-oxohexanoate + NADP+ + H2O
RHEA:33543 ergosteryl hexadecanoate + H2O = ergosterol + hexadecanoate + H+
RHEA:33547 lanosteryl hexadecanoate + H2O = lanosterol + hexadecanoate + H+
RHEA:33551 an N-acylsphinganine + H2O = sphinganine + a fatty acid
2,731 protein(s) (UniProtKB)
RHEA:33555 an N-acyl-(4R)-4-hydroxysphinganine + H2O = (4R)-hydroxysphinganine + a fatty acid
4 protein(s) (UniProtKB)