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Results (104 reactions)

RHEA:24112 2 glutathione + O2 = glutathione disulfide + H2O2
RHEA:24424 L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate
  • EC:1.8.5.1 glutathione dehydrogenase (ascorbate)
4,086 protein(s) (UniProtKB)
RHEA:25245 (R)-S-lactoylglutathione + H2O = (R)-lactate + glutathione + H+ 1,062 protein(s) (UniProtKB)
RHEA:28655 glutathione S,S-dioxide + H2O = sulfite + glutathione + H+
RHEA:28807 glutathione + H2O = L-cysteinylglycine + L-glutamate 34,859 protein(s) (UniProtKB)
RHEA:29787 glutathione(in) + ATP + H2O = glutathione(out) + ADP + phosphate + H+
6 protein(s) (UniProtKB)
RHEA:29791 glutathione(out) + ATP + H2O = glutathione(in) + ADP + phosphate + H+ 8,961 protein(s) (UniProtKB)
RHEA:34903 selenite + 4 glutathione + 2 H+ = selenodiglutathione + glutathione disulfide + 3 H2O
RHEA:34927 selenodiglutathione + NADPH + H+ = glutathioselenol + glutathione + NADP+
RHEA:34931 glutathioselenol + NADPH = hydrogenselenide + glutathione + NADP+
RHEA:40719 apo-[alkylcobalamin reductase] + an R-cob(III)alamin + glutathione = cob(I)alamin-[alkylcobalamin reductase] + an S-substituted glutathione + H+ 837 protein(s) (UniProtKB)
RHEA:47724 glutathione = L-cysteinylglycine + 5-oxo-L-proline
  • EC:4.3.2.7 glutathione-specific gamma-glutamylcyclotransferase
2,860 protein(s) (UniProtKB)
RHEA:48620 (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + glutathione disulfide + H2O
1,109 protein(s) (UniProtKB)
RHEA:48888 (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O
641 protein(s) (UniProtKB)
RHEA:49568 2-glutathionyl-2-methylbut-3-en-1-ol = (3R)-3,4-epoxy-3-methylbut-1-ene + glutathione
  • EC:4.4.1.34 isoprene-epoxide--glutathione S-transferase
1 protein(s) (UniProtKB)
RHEA:50260 11(S)-hydroxy-14(S),15(S)-epoxy-(5Z,8Z,12E)-eicosatrienoate + glutathione = (11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoate
23 protein(s) (UniProtKB)
RHEA:50708 (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O
1,241 protein(s) (UniProtKB)
RHEA:50796 prostaglandin A2 + glutathione = prostaglandin A2-S-(R)-glutathione
15 protein(s) (UniProtKB)
RHEA:50800 prostaglandin A2 + glutathione = prostaglandin A2-S-(S)-glutathione
17 protein(s) (UniProtKB)
RHEA:50804 prostaglandin J2 + glutathione = prostaglandin J2-S-(R)-glutathione
26 protein(s) (UniProtKB)
RHEA:50808 prostaglandin J2 + glutathione = prostaglandin J2-S-(S)-glutathione
17 protein(s) (UniProtKB)
RHEA:51220 1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H+ 1,100 protein(s) (UniProtKB)
RHEA:51936 2-(glutathione-S-yl)-hydroquinone + glutathione = hydroquinone + glutathione disulfide 2 protein(s) (UniProtKB)
RHEA:51992 an (E)-ω-(methylsulfanyl)-alkanal oxime + glutathione + reduced [NADPH—hemoprotein reductase] + O2 = an S-[(1E)-1-(hydroxyimino)-ω-(methylsulfanyl)alkyl]-L-glutathione + oxidized [NADPH—hemoprotein reductase] + 2 H2O + H+ 1 protein(s) (UniProtKB)
RHEA:52000 a (1E)-1-aci-nitro-ω-(methylsulfanyl)alkane + glutathione = an S-[(1E)-1-(hydroxyimino)-ω-(methylsulfanyl)alkyl]-L-glutathione + H2O
RHEA:52180 (E)-(indol-3-yl)acetaldehyde oxime + glutathione + reduced [NADPH—hemoprotein reductase] + O2 = (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + oxidized [NADPH—hemoprotein reductase] + 2 H2O + H+ 1 protein(s) (UniProtKB)
RHEA:52188 1-aci-nitro-2-(1H-indol-3-yl)ethane + glutathione = (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + H2O
RHEA:52192 (E)-phenylacetaldehyde oxime + glutathione + reduced [NADPH—hemoprotein reductase] + O2 = (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + oxidized [NADPH—hemoprotein reductase] + 2 H2O + H+ 1 protein(s) (UniProtKB)
RHEA:52200 1-aci-nitro-2-(phenyl)ethane + glutathione = (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H2O
RHEA:53012 2,5-dichlorohydroquinone + 2 glutathione = chlorohydroquinone + glutathione disulfide + chloride + H+
2 protein(s) (UniProtKB)
RHEA:53016 chlorohydroquinone + 2 glutathione = hydroquinone + glutathione disulfide + chloride + H+
2 protein(s) (UniProtKB)
RHEA:53508 (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + glutathione = (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate
799 protein(s) (UniProtKB)
RHEA:55156 a quinone + hydrogen sulfide + glutathione + H+ = S-sulfanylglutathione + a quinol
  • EC:1.8.5.8 eukaryotic sulfide quinone oxidoreductase
3 protein(s) (UniProtKB)
RHEA:55976 thiosulfate + glutathione = S-sulfanylglutathione + sulfite + H+
2 protein(s) (UniProtKB)
RHEA:56828 2,3,6-trichlorohydroquinone + glutathione disulfide + chloride = 2,3,5,6-tetrachlorohydroquinone + 2 glutathione
  • EC:1.21.4.5 tetrachlorohydroquinone reductive dehalogenase
1 protein(s) (UniProtKB)
RHEA:56832 2,6-dichlorohydroquinone + glutathione disulfide + chloride + H+ = 2,3,6-trichlorohydroquinone + 2 glutathione
  • EC:1.21.4.5 tetrachlorohydroquinone reductive dehalogenase
1 protein(s) (UniProtKB)
RHEA:57080 S-methyl-1-thio-D-xylulose 5-phosphate + glutathione = S-(methylsulfanyl)glutathione + 1-deoxy-D-xylulose 5-phosphate
  • EC:2.8.4.6 S-methyl-1-thioxylulose 5-phosphate methylthiotransferase
1 protein(s) (UniProtKB)
RHEA:57092 S-(methylsulfanyl)glutathione + AH2 = methanethiol + glutathione + A
1 protein(s) (UniProtKB)
RHEA:62608 ubiquinone-10 + hydrogen sulfide + glutathione + H+ = S-sulfanylglutathione + ubiquinol-10
2 protein(s) (UniProtKB)
RHEA:62632 a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O 10,767 protein(s) (UniProtKB)
RHEA:63132 apo-[alkylcobalamin reductase] + methylcob(III)alamin + glutathione = S-methyl glutathione + cob(I)alamin-[alkylcobalamin reductase] + H+ 837 protein(s) (UniProtKB)
RHEA:63136 apo-[alkylcobalamin reductase] + adenosylcob(III)alamin + glutathione = S-adenosylglutathione + cob(I)alamin-[alkylcobalamin reductase] + H+ 837 protein(s) (UniProtKB)
RHEA:66380 glycodeoxycholate(in) + glutathione(in) + ATP + H2O = glycodeoxycholate(out) + glutathione(out) + ADP + phosphate + H+
3 protein(s) (UniProtKB)
RHEA:66396 cholate(in) + glutathione(in) + ATP + H2O = cholate(out) + glutathione(out) + ADP + phosphate + H+
3 protein(s) (UniProtKB)
RHEA:66400 glycocholate(in) + glutathione(in) + ATP + H2O = glycocholate(out) + glutathione(out) + ADP + phosphate + H+
3 protein(s) (UniProtKB)
RHEA:66404 taurocholate(in) + glutathione(in) + ATP + H2O = taurocholate(out) + glutathione(out) + ADP + phosphate + H+
3 protein(s) (UniProtKB)
RHEA:66408 glycochenodeoxycholate(in) + glutathione(in) + ATP + H2O = glycochenodeoxycholate(out) + glutathione(out) + ADP + phosphate + H+
3 protein(s) (UniProtKB)
RHEA:66412 taurochenodeoxycholate(in) + glutathione(in) + ATP + H2O = taurochenodeoxycholate(out) + glutathione(out) + ADP + phosphate + H+
3 protein(s) (UniProtKB)
RHEA:66416 glycoursodeoxycholate(in) + glutathione(in) + ATP + H2O = glycoursodeoxycholate(out) + glutathione(out) + ADP + phosphate + H+
3 protein(s) (UniProtKB)
RHEA:66420 tauroursodeoxycholate(in) + glutathione(in) + ATP + H2O = tauroursodeoxycholate(out) + glutathione(out) + ADP + phosphate + H+
3 protein(s) (UniProtKB)
RHEA:69412 tert-butyl hydroperoxide + 2 glutathione = tert-butanol + glutathione disulfide + H2O
226 protein(s) (UniProtKB)
RHEA:69428 arsenite + 3 glutathione + H+ = arsenic triglutathione + 3 H2O
RHEA:69432 arsenic triglutathione + 3 [thioredoxin]-dithiol + 3 S-adenosyl-L-methionine = trimethylarsine + 3 [thioredoxin]-disulfide + 3 glutathione + 3 S-adenosyl-L-homocysteine + 3 H+ 16,860 protein(s) (UniProtKB)
RHEA:69460 arsenic triglutathione + [thioredoxin]-dithiol + S-adenosyl-L-methionine + 2 H2O = methylarsonous acid + [thioredoxin]-disulfide + 3 glutathione + S-adenosyl-L-homocysteine + H+ 16,860 protein(s) (UniProtKB)
RHEA:69464 arsenic triglutathione + 2 [thioredoxin]-dithiol + 2 S-adenosyl-L-methionine + H2O = dimethylarsinous acid + 2 [thioredoxin]-disulfide + 3 glutathione + 2 S-adenosyl-L-homocysteine + 2 H+ 16,860 protein(s) (UniProtKB)
RHEA:69651 cumene hydroperoxide + 2 glutathione = 2-phenylpropan-2-ol + glutathione disulfide + H2O
114 protein(s) (UniProtKB)
RHEA:71975 glutathione(out) + 3 Na+(out) = glutathione(in) + 3 Na+(in)
RHEA:72011 urate(out) + glutathione(in) = urate(in) + glutathione(out)
1 protein(s) (UniProtKB)
RHEA:72311 taurocholate(out) + glutathione(in) = taurocholate(in) + glutathione(out)
RHEA:72315 leukotriene C4(out) + glutathione(in) = leukotriene C4(in) + glutathione(out)
RHEA:74819 glutathione(in) = glutathione(out)
2,312 protein(s) (UniProtKB)
RHEA:75699 2 glutathione + NAD+ = glutathione disulfide + NADH + H+
RHEA:75835 (5S)-hydroperoxy-(6E,8Z)-octadecadienoate + 2 glutathione = (5S)-hydroxy-(6E,8Z)-octadecadienoate + glutathione disulfide + H2O
RHEA:75963 15-deoxy-Δ12,14-prostaglandin J2 + glutathione = 15-deoxy-Δ12,14-prostaglandin J2-S-(R)-glutathione
3 protein(s) (UniProtKB)
RHEA:76687 (9S)-hydroperoxy-(10E,12Z)-octadecadienoate + 2 glutathione = (9S)-hydroxy-(10E,12Z)-octadecadienoate + glutathione disulfide + H2O
20 protein(s) (UniProtKB)
RHEA:76691 (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O
112 protein(s) (UniProtKB)
RHEA:76695 (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + 2 glutathione = (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + glutathione disulfide + H2O
112 protein(s) (UniProtKB)
RHEA:76699 (5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O
20 protein(s) (UniProtKB)
RHEA:76703 (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O
19 protein(s) (UniProtKB)
RHEA:76707 (15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + 2 glutathione = (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + glutathione disulfide + H2O
20 protein(s) (UniProtKB)
RHEA:76711 (15S)-hydroperoxy-(11Z,13E)-eicosadienoate + 2 glutathione = (15S)-hydroxy-(11Z,13E)-eicosadienoate + glutathione disulfide + H2O
20 protein(s) (UniProtKB)
RHEA:76715 (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + 2 glutathione = (17S)-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + glutathione disulfide + H2O
20 protein(s) (UniProtKB)
RHEA:76731 a hydroperoxy-1,2-diacyl-glycero-3-phosphocholine + 2 glutathione = a hydroxy-1,2-diacyl-glycero-3-phosphocholine + glutathione disulfide + H2O
9 protein(s) (UniProtKB)
RHEA:79851 S-sulfanylglutathione + glutathione = glutathione disulfide + hydrogen sulfide + H+
RHEA:80519 2,4,6-trinitrotoluene + glutathione = S-(4,6-dinitrotoluyl)glutathione + nitrite + H+
RHEA:80523 2,4,6-trinitrotoluene + glutathione + AH2 = S-(2,6-dinitro-4-hydroxylaminotoluyl)glutathione + A + H2O
RHEA:80531 2,4,6-trinitrotoluene + glutathione + AH2 = S-(2,4-dinitro-6-hydroxylaminotoluyl)glutathione + A + H2O
RHEA:10720 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O = 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione 1 protein(s) (UniProtKB)
RHEA:11464 L,L-homocystine + 2 glutathione = 2 L-homocysteine + glutathione disulfide
  • EC:1.8.4.1 glutathione--homocystine transhydrogenase
RHEA:11740 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+ 8,321 protein(s) (UniProtKB)
RHEA:12613 L-cystine + 2 glutathione = glutathione disulfide + 2 L-cysteine
  • EC:1.8.4.4 glutathione--cystine transhydrogenase
RHEA:12981 S-sulfanylglutathione + O2 + H2O = sulfite + glutathione + 2 H+ 4 protein(s) (UniProtKB)
RHEA:13125 glutathione disulfide + CoA = CoA-glutathione + glutathione
  • EC:1.8.4.3 glutathione--CoA-glutathione transhydrogenase
RHEA:13557 γ-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H+ 21,331 protein(s) (UniProtKB)
RHEA:14141 glutathione disulfide + sulfite + AMP + 2 H+ = adenosine 5'-phosphosulfate + 2 glutathione
  • EC:1.8.4.9 adenylyl-sulfate reductase (glutathione)
4 protein(s) (UniProtKB)
RHEA:14505 thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H+ 1 protein(s) (UniProtKB)
RHEA:14617 glutathione + NADP+ + CoA = CoA-glutathione + NADPH + H+
RHEA:14961 S-formylglutathione + H2O = formate + glutathione + H+ 15,910 protein(s) (UniProtKB)
RHEA:15969 methylarsonate + 2 glutathione + H+ = methylarsonous acid + glutathione disulfide + H2O 2,227 protein(s) (UniProtKB)
RHEA:16437 RX + glutathione = an S-substituted glutathione + a halide anion + H+ 47,890 protein(s) (UniProtKB)
RHEA:16713 S-succinylglutathione + H2O = glutathione + succinate + H+
RHEA:16833 2 glutathione + H2O2 = glutathione disulfide + 2 H2O 4,419 protein(s) (UniProtKB)
RHEA:17173 glutathionylspermidine + H2O = spermidine + glutathione 2 protein(s) (UniProtKB)
RHEA:17617 leukotriene C4 = leukotriene A4 + glutathione 980 protein(s) (UniProtKB)
RHEA:17917 [Glu(-Cys)](n)-Gly + glutathione + H+ = [Glu(-Cys)](n+1)-Gly + glycine
  • EC:2.3.2.15 glutathione gamma-glutamylcysteinyltransferase
8 protein(s) (UniProtKB)
RHEA:19057 a hydroperoxy polyunsaturated fatty acid + 2 glutathione = a hydroxy polyunsaturated fatty acid + glutathione disulfide + H2O
  • EC:1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase
1,188 protein(s) (UniProtKB)
RHEA:19069 (R)-S-lactoylglutathione = methylglyoxal + glutathione 13,152 protein(s) (UniProtKB)
RHEA:21064 [protein]-disulfide + 2 glutathione = [protein]-dithiol + glutathione disulfide
  • EC:1.8.4.2 protein-disulfide reductase (glutathione)
800 protein(s) (UniProtKB)
RHEA:21272 spermidine + glutathione + ATP = glutathionylspermidine + ADP + phosphate + H+ 5 protein(s) (UniProtKB)
RHEA:21532 glutathionylspermidine + glutathione + ATP = trypanothione + ADP + phosphate + H+ 2 protein(s) (UniProtKB)