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Results (840 reactions)

RHEA:23136 a primary amine + S-adenosyl-L-methionine = a methylated primary amine + S-adenosyl-L-homocysteine + H+ 4 protein(s) (UniProtKB)
RHEA:23248 myo-inositol + S-adenosyl-L-methionine = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:23548 guanosine966 in 16S rRNA + S-adenosyl-L-methionine = N2-methylguanosine966 in 16S rRNA + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.171 16S rRNA (guanine(966)-N(2))-methyltransferase
6,390 protein(s) (UniProtKB)
RHEA:23808 (S)-scoulerine + S-adenosyl-L-methionine = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H+ 6 protein(s) (UniProtKB)
RHEA:23884 nicotinamide + S-adenosyl-L-methionine = 1-methylnicotinamide + S-adenosyl-L-homocysteine 4 protein(s) (UniProtKB)
RHEA:23908 2 methylcob(III)alamin-[methionine synthase] + 2 S-adenosyl-L-homocysteine + NADP+ + H+ = 2 cob(II)alamin-[methionine synthase] + 2 S-adenosyl-L-methionine + NADPH 5 protein(s) (UniProtKB)
RHEA:24012 γ-tocopherol + S-adenosyl-L-methionine = (+)-α-tocopherol + S-adenosyl-L-homocysteine + H+ 2 protein(s) (UniProtKB)
RHEA:24096 isoorientin + S-adenosyl-L-methionine = isoscoparin + S-adenosyl-L-homocysteine + H+
RHEA:24140 guanosine2251 in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine2251 in 23S rRNA + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.185 23S rRNA (guanosine(2251)-2'-O)-methyltransferase
7,465 protein(s) (UniProtKB)
RHEA:24312 L-lysyl-[cytochrome c] + S-adenosyl-L-methionine = N6-methyl-L-lysyl-[cytochrome c] + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.59 [cytochrome c]-lysine N-methyltransferase
17 protein(s) (UniProtKB)
RHEA:24452 L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine 30,670 protein(s) (UniProtKB)
RHEA:24604 7-methylxanthine + S-adenosyl-L-methionine = theobromine + S-adenosyl-L-homocysteine + H+ 22 protein(s) (UniProtKB)
RHEA:24726 N-demethylindolmycin + S-adenosyl-L-methionine = indolmycin + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:24894 5-hydroxyxanthotoxin + S-adenosyl-L-methionine = isopimpinellin + S-adenosyl-L-homocysteine
  • EC:2.1.1.69 5-hydroxyfuranocoumarin 5-O-methyltransferase
RHEA:25269 (R)-noradrenaline + S-adenosyl-L-methionine = (R)-adrenaline + S-adenosyl-L-homocysteine + H+ 189 protein(s) (UniProtKB)
RHEA:25321 N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H+ 2,817 protein(s) (UniProtKB)
RHEA:25325 N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine = phosphocholine + S-adenosyl-L-homocysteine + H+ 2,817 protein(s) (UniProtKB)
RHEA:25629 myricetin + S-adenosyl-L-methionine = laricitrin + S-adenosyl-L-homocysteine + H+ 2 protein(s) (UniProtKB)
RHEA:25633 laricitrin + S-adenosyl-L-methionine = syringetin + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:26273 Co-precorrin-3 + S-adenosyl-L-methionine = Co-precorrin-4 + S-adenosyl-L-homocysteine
RHEA:26277 Co-precorrin-4 + S-adenosyl-L-methionine = Co-precorrin-5A + S-adenosyl-L-homocysteine + H+ 4 protein(s) (UniProtKB)
RHEA:26285 Co-precorrin-5B + S-adenosyl-L-methionine = Co-precorrin-6A + S-adenosyl-L-homocysteine 9,755 protein(s) (UniProtKB)
RHEA:26321 resorcinol + S-adenosyl-L-methionine = 3-methoxyphenol + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:26325 (8Z,11Z)-5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine = (8Z,11Z)-5-(pentadeca- 8,11,14-trien-1-yl)resorcinol-3-methyl ether + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.n7 5-pentadecatrienyl resorcinol O-methyltransferase
1 protein(s) (UniProtKB)
RHEA:26462 6-methoxy-2-all-trans-octaprenyl-1,4-benzoquinone + S-adenosyl-L-methionine = 2-methoxy-5-methyl-6-all-trans-octaprenyl-1,4-benzoquinone + S-adenosyl-L-homocysteine + H+
RHEA:26466 a 2-demethylmenaquinone + S-adenosyl-L-methionine = a menaquinone + S-adenosyl-L-homocysteine + H+
RHEA:27353 4'-demethylrebeccamycin + S-adenosyl-L-methionine = rebeccamycin + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.164 demethylrebeccamycin-D-glucose O-methyltransferase
1 protein(s) (UniProtKB)
RHEA:27357 iodide + S-adenosyl-L-methionine = iodomethane + S-adenosyl-L-homocysteine
RHEA:27361 chloride + S-adenosyl-L-methionine = chloromethane + S-adenosyl-L-homocysteine
RHEA:27365 bromide + S-adenosyl-L-methionine = bromomethane + S-adenosyl-L-homocysteine
RHEA:27493 tricetin + S-adenosyl-L-methionine = 3'-O-methyltricetin + S-adenosyl-L-homocysteine + H+
1 protein(s) (UniProtKB)
RHEA:27497 3'-O-methyltricetin + S-adenosyl-L-methionine = 3',5'-di-O-methyltricetin + S-adenosyl-L-homocysteine + H+
RHEA:27501 3',5'-di-O-methyltricetin + S-adenosyl-L-methionine = 3',4',5'-O-trimethyltricetin + S-adenosyl-L-homocysteine + H+
RHEA:27770 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine + H+
RHEA:27774 2-methoxy-6-(all-trans-octaprenyl)benzene-1,4-diol + S-adenosyl-L-methionine = 5-methoxy-2-methyl-3-(all-trans-octaprenyl)benzene-1,4-diol + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.201 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase
RHEA:28014 thiocyanate + S-adenosyl-L-methionine = methyl thiocyanate + S-adenosyl-L-homocysteine 3 protein(s) (UniProtKB)
RHEA:28286 a 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + S-adenosyl-L-methionine = a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzene-1,4-diol + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.201 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase
16,584 protein(s) (UniProtKB)
RHEA:28679 3-demethylubiquinol-8 + S-adenosyl-L-methionine = ubiquinol-8 + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.64 3-demethylubiquinol 3-O-methyltransferase
RHEA:30063 2-demethylmenaquinol-8 + S-adenosyl-L-methionine = menaquinol-8 + S-adenosyl-L-homocysteine + H+
RHEA:30903 demethylspheroidene + S-adenosyl-L-methionine = spheroidene + S-adenosyl-L-homocysteine + H+ 3 protein(s) (UniProtKB)
RHEA:31371 (2R,3S)-2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine = (2R,3S)-2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.212 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase
3 protein(s) (UniProtKB)
RHEA:31411 a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + S-adenosyl-L-homocysteine + H+ 13,171 protein(s) (UniProtKB)
RHEA:31539 (2S)-naringenin + S-adenosyl-L-methionine = (2S)-sakuranetin + S-adenosyl-L-homocysteine + H+ 5 protein(s) (UniProtKB)
RHEA:31615 dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose + 2 S-adenosyl-L-methionine = dTDP-D-ravidosamine + 2 S-adenosyl-L-homocysteine + 2 H+
  • EC:2.1.1.236 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase
RHEA:31623 L-olivosyl-oleandolide + S-adenosyl-L-methionine = L-oleandrosyl-oleandolide + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:31639 mycinamicin III + S-adenosyl-L-methionine = mycinamicin IV + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:31643 mycinamicin VI + S-adenosyl-L-methionine = mycinamicin III + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:31671 dTDP-3-amino-3,6-dideoxy-α-D-glucose + 2 S-adenosyl-L-methionine = dTDP-α-D-mycaminose + 2 S-adenosyl-L-homocysteine + 2 H+
  • EC:2.1.1.235 dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
1 protein(s) (UniProtKB)
RHEA:31739 a 4'-hydroxyisoflavone + S-adenosyl-L-methionine = a 4'-methoxyisoflavone + S-adenosyl-L-homocysteine + H+ 4 protein(s) (UniProtKB)
RHEA:31743 a 4'-hydroxyflavanone + S-adenosyl-L-methionine = a 4'-methoxyflavanone + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:31759 dTDP-3-amino-3,4,6-trideoxy-α-D-glucose + 2 S-adenosyl-L-methionine = dTDP-α-D-desosamine + 2 S-adenosyl-L-homocysteine + 2 H+
  • EC:2.1.1.234 dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
1 protein(s) (UniProtKB)
RHEA:31907 (S)-norcoclaurine + S-adenosyl-L-methionine = (S)-coclaurine + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:32099 TRIBOA β-D-glucoside + S-adenosyl-L-methionine = DIMBOA β-D-glucoside + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.241 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase
1 protein(s) (UniProtKB)
RHEA:32103 trans-resveratrol + 2 S-adenosyl-L-methionine = pterostilbene + 2 S-adenosyl-L-homocysteine + 2 H+ 1 protein(s) (UniProtKB)
RHEA:32107 3-methoxy-4',5-dihydroxy-trans-stilbene + S-adenosyl-L-methionine = pterostilbene + S-adenosyl-L-homocysteine + H+
RHEA:32111 trans-resveratrol + S-adenosyl-L-methionine = 3-methoxy-4',5-dihydroxy-trans-stilbene + S-adenosyl-L-homocysteine + H+
1 protein(s) (UniProtKB)
RHEA:32291 phosphoethanolamine + 3 S-adenosyl-L-methionine = phosphocholine + 3 S-adenosyl-L-homocysteine + 3 H+
RHEA:32347 tricetin + 2 S-adenosyl-L-methionine = 3',5'-di-O-methyltricetin + 2 S-adenosyl-L-homocysteine + 2 H+ 3 protein(s) (UniProtKB)
RHEA:32351 tricetin + 3 S-adenosyl-L-methionine = 3',4',5'-O-trimethyltricetin + 3 S-adenosyl-L-homocysteine + 3 H+ 1 protein(s) (UniProtKB)
RHEA:32459 uroporphyrinogen III + 2 S-adenosyl-L-methionine = precorrin-2 + 2 S-adenosyl-L-homocysteine + H+ 5,561 protein(s) (UniProtKB)
RHEA:32463 glycine + 2 S-adenosyl-L-methionine = N,N-dimethylglycine + 2 S-adenosyl-L-homocysteine + 2 H+ 4 protein(s) (UniProtKB)
RHEA:32467 sarcosine + 2 S-adenosyl-L-methionine = glycine betaine + 2 S-adenosyl-L-homocysteine + 2 H+
  • EC:2.1.1.157 sarcosine/dimethylglycine N-methyltransferase
3 protein(s) (UniProtKB)
RHEA:32475 glycine + 3 S-adenosyl-L-methionine = glycine betaine + 3 S-adenosyl-L-homocysteine + 3 H+
  • EC:2.1.1.162 glycine/sarcosine/dimethylglycine N-methyltransferase
RHEA:32519 (2E)-geranyl diphosphate + S-adenosyl-L-methionine = (E)-2-methylgeranyl diphosphate + S-adenosyl-L-homocysteine + H+ 4 protein(s) (UniProtKB)
RHEA:32647 erythromycin C + S-adenosyl-L-methionine = erythromycin A + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:32651 erythromycin D + S-adenosyl-L-methionine = erythromycin B + S-adenosyl-L-homocysteine + H+ 1 protein(s) (UniProtKB)
RHEA:32663 5-guanidino-2-oxopentanoate + S-adenosyl-L-methionine = (3R)-5-guanidino-3-methyl-2-oxopentanoate + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.243 5-guanidino-2-oxopentanoate (3R)-methyltransferase
2 protein(s) (UniProtKB)
RHEA:32735 a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.71 phosphatidyl-N-methylethanolamine N-methyltransferase
2,648 protein(s) (UniProtKB)
RHEA:32739 a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.71 phosphatidyl-N-methylethanolamine N-methyltransferase
2,648 protein(s) (UniProtKB)
RHEA:32767 cytidine4 in tRNAPro + S-adenosyl-L-methionine = 2'-O-methylcytidine4 in tRNAPro + S-adenosyl-L-homocysteine + H+ 3,159 protein(s) (UniProtKB)
RHEA:33255 2-demethylmenaquinol-7 + S-adenosyl-L-methionine = menaquinol-7 + S-adenosyl-L-homocysteine + H+
RHEA:34007 7-dehydrodesmosterol + S-adenosyl-L-methionine = 5-dehydroepisterol + S-adenosyl-L-homocysteine + H+
RHEA:34435 4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine = 4-(3-methylbut-2-enyl)-L-abrine + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.261 4-dimethylallyltryptophan N-methyltransferase
478 protein(s) (UniProtKB)
RHEA:34539 tellurite + S-adenosyl-L-methionine = methanetellurite + S-adenosyl-L-homocysteine 1 protein(s) (UniProtKB)
RHEA:34591 Co-precorrin-7 + S-adenosyl-L-methionine = Co-precorrin-8X + S-adenosyl-L-homocysteine + H+ 4 protein(s) (UniProtKB)
RHEA:34643 squalene + 2 S-adenosyl-L-methionine = 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene + 2 S-adenosyl-L-homocysteine + 2 H+ 2 protein(s) (UniProtKB)
RHEA:34647 squalene + S-adenosyl-L-methionine = 3-methyl-1,2-didehydro-2,3-dihydrosqualene + S-adenosyl-L-homocysteine + H+
RHEA:34651 3-methyl-1,2-didehydro-2,3-dihydrosqualene + S-adenosyl-L-methionine = 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene + S-adenosyl-L-homocysteine + H+
RHEA:34655 C30 botryococcene + 2 S-adenosyl-L-methionine = 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + 2 S-adenosyl-L-homocysteine + 2 H+ 1 protein(s) (UniProtKB)
RHEA:34659 C30 botryococcene + S-adenosyl-L-methionine = 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + S-adenosyl-L-homocysteine + H+
RHEA:34663 20-methyl-21,22-didehydro-20,21-dihydrobotryococcene + S-adenosyl-L-methionine = 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + S-adenosyl-L-homocysteine + H+
RHEA:34667 C30 botryococcene + S-adenosyl-L-methionine = 20-methyl-21,22-didehydro-20,21-dihydrobotryococcene + S-adenosyl-L-homocysteine + H+
RHEA:34671 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + S-adenosyl-L-methionine = 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + S-adenosyl-L-homocysteine + H+
RHEA:34899 malonyl-CoA + S-adenosyl-L-methionine = malonyl-CoA methyl ester + S-adenosyl-L-homocysteine
RHEA:35091 anthranilate + L-phenylalanine + S-adenosyl-L-methionine + 2 ATP = cyclopeptine + 2 AMP + S-adenosyl-L-homocysteine + 2 diphosphate + 2 H+ 2 protein(s) (UniProtKB)
RHEA:35383 precorrin-6B + S-adenosyl-L-methionine = precorrin-7 + S-adenosyl-L-homocysteine + CO2 + H+
RHEA:35387 precorrin-7 + S-adenosyl-L-methionine = precorrin-8X + S-adenosyl-L-homocysteine + 2 H+
RHEA:35471 (+)-6a-hydroxymaackiain + S-adenosyl-L-methionine = (+)-pisatin + S-adenosyl-L-homocysteine + H+
  • EC:2.1.1.270 (+)-6a-hydroxymaackiain 3-O-methyltransferase
2 protein(s) (UniProtKB)
RHEA:35483 5α-cholest-7-en-3-one + S-adenosyl-L-methionine = 4α-methyl-5α-cholest-7-en-3-one + S-adenosyl-L-homocysteine + H+
1 protein(s) (UniProtKB)
RHEA:35767 dihydrosterigmatocystin + S-adenosyl-L-methionine = 8-O-methyldihydrosterigmatocystin + S-adenosyl-L-homocysteine + H+ 2 protein(s) (UniProtKB)
RHEA:36067 Co-precorrin-6B + S-adenosyl-L-methionine = Co-precorrin-7 + S-adenosyl-L-homocysteine + CO2
  • EC:2.1.1.196 cobalt-precorrin-6B (C(15))-methyltransferase [decarboxylating]
567 protein(s) (UniProtKB)
RHEA:36095 salicylate + S-adenosyl-L-methionine = methyl salicylate + S-adenosyl-L-homocysteine 5 protein(s) (UniProtKB)
RHEA:36099 benzoate + S-adenosyl-L-methionine = methyl benzoate + S-adenosyl-L-homocysteine 7 protein(s) (UniProtKB)
RHEA:36103 anthranilate + S-adenosyl-L-methionine = O-methyl anthranilate + S-adenosyl-L-homocysteine 3 protein(s) (UniProtKB)
RHEA:36107 gibberellin A4 + S-adenosyl-L-methionine = O-methyl gibberellin A4 + S-adenosyl-L-homocysteine 1 protein(s) (UniProtKB)
RHEA:36111 gibberellin A1 + S-adenosyl-L-methionine = O-methyl gibberellin A1 + S-adenosyl-L-homocysteine
RHEA:36115 gibberellin A3 + S-adenosyl-L-methionine = O-methyl gibberellin A3 + S-adenosyl-L-homocysteine
RHEA:36119 gibberellin A9 + S-adenosyl-L-methionine = O-methyl gibberellin A9 + S-adenosyl-L-homocysteine 1 protein(s) (UniProtKB)
RHEA:36123 gibberellin A20 + S-adenosyl-L-methionine = gibberellin A20 methyl ester + S-adenosyl-L-homocysteine
RHEA:36127 gibberellin A34 + S-adenosyl-L-methionine = O-methyl gibberellin A34 + S-adenosyl-L-homocysteine