Rhea - reaction knowledgebase

Reaction participants Show >> << Hide

Name ^help_outline alcohol glucuronate acceptor Identifier CHEBI:149480 Charge 0 Formula HOR SMILES^help_outline O* 2D coordinates Mol file for the small molecule Search links Involved in 1 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline UDP-α-D-glucuronate Identifier CHEBI:58052 Charge -3 Formula C15H19N2O18P2 InChIKey^help_outline HDYANYHVCAPMJV-LXQIFKJMSA-K SMILES^help_outline O[C@@H]1[C@@H](COP([O-])(=O)OP([O-])(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C([O-])=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O 2D coordinates Mol file for the small molecule Search links Involved in 107 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline a β-D-glucuronoside Identifier CHEBI:83411 Charge -1 Formula C6H8O7R SMILES^help_outline O[C@@H]1[C@@H](O)[C@H](O[*])O[C@@H]([C@H]1O)C([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 63 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline UDP Identifier CHEBI:58223 Charge -3 Formula C9H11N2O12P2 InChIKey^help_outline XCCTYIAWTASOJW-XVFCMESISA-K SMILES^help_outline O[C@@H]1[C@@H](COP([O-])(=O)OP([O-])([O-])=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O 2D coordinates Mol file for the small molecule Search links Involved in 577 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline H⁺ Identifier CHEBI:15378 Charge 1 Formula H InChIKey^help_outline GPRLSGONYQIRFK-UHFFFAOYSA-N SMILES^help_outline [H+] 2D coordinates Mol file for the small molecule Search links Involved in 9,521 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule

Cross-references

	RHEA:63692	RHEA:63693	RHEA:63694	RHEA:63695
Reaction direction	undefined	left-to-right	right-to-left	bidirectional
UniProtKB ^help_outline

Related reactions ^help_outline

Specific form(s) of this reaction

RHEA:74565
aldosterone hemiacetal 18-β-glucuronide + UDP + H⁺ => aldosterone hemiacetal + UDP-α-D-glucuronate
RHEA:63734
zolarsartan O-β-D-glucuronoside + UDP => zolasartan + UDP-α-D-glucuronate
RHEA:63726
candesartan O-β-D-glucuronoside + UDP => candesartan + UDP-α-D-glucuronate
RHEA:63706
mycophenolate 7-O-β-D-glucuronide + UDP + H⁺ => mycophenolate + UDP-α-D-glucuronate
RHEA:63702
mycophenolic acid O-acyl-β-D-glucuronide + UDP => mycophenolate + UDP-α-D-glucuronate
RHEA:63698
SN-38 O-β-D-glucuronide + UDP + H⁺ => SN-38 + UDP-α-D-glucuronate
RHEA:63614
prunetin-5-O-β-D-glucuronide + UDP => prunetin + UDP-α-D-glucuronate
RHEA:63590
prunetin-4'-O-β-D-glucuronide + UDP => prunetin + UDP-α-D-glucuronate
RHEA:56510
3-O-[β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-2-O-P-Xyl]-L-seryl-[protein] + UDP + H⁺ => 3-O-(β-D-galactosyl-(1→3)-β-D-galactosyl-(1→4)-β-D-2-O-phosphoxylosyl)-L-seryl-[protein] + UDP-α-D-glucuronate
RHEA:56162
an archaeal dolichyl β-D-glucuronosyl-(1→4)-α-D-glucosyl phosphate + UDP + H⁺ => an archaeal dolichyl α-D-glucosyl phosphate + UDP-α-D-glucuronate
RHEA:55846
calcidiol 3-O-(β-D-glucuronide) + UDP + H⁺ => calcidiol + UDP-α-D-glucuronate
RHEA:55842
calcidiol 25-O-(β-D-glucuronide) + UDP + H⁺ => calcidiol + UDP-α-D-glucuronate
RHEA:55838
calcitriol 25-O-(β-D-glucuronide) + UDP + H⁺ => calcitriol + UDP-α-D-glucuronate
RHEA:55786
all-trans-4-oxoretinoate 1-O-(β-D-glucuronate) + UDP => all-trans-4-oxoretinoate + UDP-α-D-glucuronate
RHEA:55782
all-trans-5,6-epoxyretinoyl-1-O-(β-D-glucuronate) + UDP => all-trans-5,6-epoxyretinoate + UDP-α-D-glucuronate
RHEA:55778
all-trans-4-hydroxy-4-O-(β-D-glucuronide)-retinoate + UDP + H⁺ => all-trans-4-hydroxyretinoate + UDP-α-D-glucuronate
RHEA:55770
all-trans-retinoyl-1-O-(β-D-glucuronate) + UDP => all-trans-retinoate + UDP-α-D-glucuronate
RHEA:53390
5α-dihydrotestosterone 17-O-[β-D-glucuronosyl-(1→2)-glucuronate] + UDP + H⁺ => 5α-dihydrotestosterone 17-O-(β-D-glucuronate) + UDP-α-D-glucuronate
RHEA:53082
4-methoxy-17β-estradiol 3-O-(β-D-glucuronate) + UDP + H⁺ => 4-methoxy-17β-estradiol + UDP-α-D-glucuronate
RHEA:53074
2-methoxy-17β-estradiol 3-O-(β-D-glucuronate) + UDP + H⁺ => 2-methoxy-17β-estradiol + UDP-α-D-glucuronate
RHEA:53070
4-methoxyestrone 3-O-(β-D-glucuronate) + UDP + H⁺ => 4-methoxyestrone + UDP-α-D-glucuronate
RHEA:53066
2-methoxyestrone 3-O-(β-D-glucuronate) + UDP + H⁺ => 2-methoxyestrone + UDP-α-D-glucuronate
RHEA:53062
estrone 4-O-(β-D-glucuronate) + UDP + H⁺ => 4-hydroxyestrone + UDP-α-D-glucuronate
RHEA:53054
4-hydroxyestrone 3-O-(β-D-glucuronate) + UDP + H⁺ => 4-hydroxyestrone + UDP-α-D-glucuronate
RHEA:53050
2-hydroxyestrone 3-O-(β-D-glucuronate) + UDP + H⁺ => 2-hydroxyestrone + UDP-α-D-glucuronate
RHEA:53042
17β-estradiol 4-O-(β-D-glucuronate) + UDP + H⁺ => 4-hydroxy-17β-estradiol + UDP-α-D-glucuronate
RHEA:53038
4-hydroxy-17β-estradiol 3-O-(β-D-glucuronate) + UDP + H⁺ => 4-hydroxy-17β-estradiol + UDP-α-D-glucuronate
RHEA:53034
17β-estradiol 2-O-(β-D-glucuronate) + UDP + H⁺ => 2-hydroxy-17β-estradiol + UDP-α-D-glucuronate
RHEA:53030
lithocholoyl-3-O-(β-D-glucuronate) + UDP + H⁺ => lithocholate + UDP-α-D-glucuronate
RHEA:53006
2-hydroxy-17β-estradiol 3-O-(β-D-glucuronate) + UDP + H⁺ => 2-hydroxy-17β-estradiol + UDP-α-D-glucuronate
RHEA:53002
5α-dihydrotestosterone 17-O-(β-D-glucuronate) + UDP + H⁺ => 17β-hydroxy-5α-androstan-3-one + UDP-α-D-glucuronate
RHEA:52970
hyocholate 6-O-(β-D-glucuronate) + UDP + H⁺ => hyocholate + UDP-α-D-glucuronate
RHEA:52966
hyodeoxycholate 6-O-(β-D-glucuronate) + UDP + H⁺ => hyodeoxycholate + UDP-α-D-glucuronate
RHEA:52962
hyocholoyl-24-O-(β-D-glucuronate) + UDP => hyocholate + UDP-α-D-glucuronate
RHEA:52958
hyodeoxycholoyl-24-O-(β-D-glucuronate) + UDP => hyodeoxycholate + UDP-α-D-glucuronate
RHEA:52954
lithocholoyl-24-O-(β-D-glucuronate) + UDP => lithocholate + UDP-α-D-glucuronate
RHEA:52950
deoxycholoyl-24-O-(β-D-glucuronate) + UDP => deoxycholate + UDP-α-D-glucuronate
RHEA:52946
choloyl-24-O-(β-D-glucuronate) + UDP => cholate + UDP-α-D-glucuronate
RHEA:52942
chenodeoxycholoyl-24-O-(β-D-glucuronate) + UDP => chenodeoxycholate + UDP-α-D-glucuronate
RHEA:52926
16α,17α-estriol 3-O-(β-D-glucuronate) + UDP + H⁺ => 16α,17α-estriol + UDP-α-D-glucuronate
RHEA:52922
16α,17α-estriol 16-O-(β-D-glucuronate) + UDP + H⁺ => 16α,17α-estriol + UDP-α-D-glucuronate
RHEA:52918
16α,17α-estriol 17-O-(β-D-glucuronate) + UDP + H⁺ => 16α,17α-estriol + UDP-α-D-glucuronate
RHEA:52882
16β,17β-estriol 16-O-(β-D-glucuronate) + UDP + H⁺ => 16β,17β-estriol + UDP-α-D-glucuronate
RHEA:52478
estrone 3-O-(β-D-glucuronate) + UDP + H⁺ => estrone + UDP-α-D-glucuronate
RHEA:52474
16α,17β-estriol 16-O-(β-D-glucuronate) + UDP + H⁺ => 16α,17β-estriol + UDP-α-D-glucuronate
RHEA:52470
16α,17β-estriol 3-O-(β-D-glucuronate) + UDP + H⁺ => 16α,17β-estriol + UDP-α-D-glucuronate
RHEA:52466
17β-estradiol 17-O-(β-D-glucuronate) + UDP + H⁺ => 17β-estradiol + UDP-α-D-glucuronate
RHEA:52462
17β-estradiol 3-O-(β-D-glucuronate) + UDP + H⁺ => 17β-estradiol + UDP-α-D-glucuronate
RHEA:52458
testosterone 17-O-(β-D-glucuronate) + UDP + H⁺ => testosterone + UDP-α-D-glucuronate
RHEA:52454
16α-hydroxyestrone 16-O-(β-D-glucuronate) + UDP + H⁺ => 16α-hydroxyestrone + UDP-α-D-glucuronate
RHEA:52450
16α-hydroxyestrone 3-O-(β-D-glucuronate) + UDP + H⁺ => 16α-hydroxyestrone + UDP-α-D-glucuronate
RHEA:31485
soyasapogenol E 3-O-β-D-glucuronate + UDP + H⁺ => soyasapogenol E + UDP-α-D-glucuronate
RHEA:30633
β-D-GlcA-(1→2)-α-D-Man-(1→3)-β-D-Glc-(1→4)-α-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H⁺ => α-D-Man-(1→3)-β-D-Glc-(1→4)-α-D-Glc-1-di-trans,octa-cis-undecaprenyl diphosphate + UDP-α-D-glucuronate
RHEA:28324
wogonin 7-O-β-D-glucuronate + UDP => wogonin + UDP-α-D-glucuronate
RHEA:28316
baicalin + UDP => baicalein + UDP-α-D-glucuronate
RHEA:28260
cyanidin 3-O-(2-O-β-D-glucuronosyl)-β-D-glucoside + UDP + H⁺ => cyanidin 3-O-β-D-glucoside + UDP-α-D-glucuronate
RHEA:24170
3-O-(β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP + H⁺ => 3-O-(β-D-galactosyl-(1→3)-β-D-galactosyl-(1→4)-β-D-xylosyl)-L-seryl-[protein] + UDP-α-D-glucuronate
RHEA:22118
luteolin 7-O-[(β-D-glucuronosyl)-(1→2)-(β-D-glucuronide)] 4'-O-β-D-glucuronide + UDP + H⁺ => luteolin 7-O-[(β-D-glucuronosyl)-(1→2)-(β-D-glucuronide)] + UDP-α-D-glucuronate
RHEA:14151
luteolin 7-O-[(β-D-glucuronosyl)-(1→2)-(β-D-glucuronide)] + UDP + H⁺ => luteolin 7-O-β-D-glucuronide + UDP-α-D-glucuronate
RHEA:10570
luteolin 7-O-β-D-glucuronide + UDP + H⁺ => luteolin + UDP-α-D-glucuronate

More general form(s) of this reaction

RHEA:21034
acceptor β-D-glucuronoside + UDP + H⁺ => glucuronate acceptor + UDP-α-D-glucuronate

RHEA:63694 a beta-D-glucuronoside + UDP + H(+) => alcohol glucuronate acceptor + UDP-alpha-D-glucuronate Reaction with net flow from right to left. help_outline

Reaction participants Show >> << Hide

Cross-references

Related reactions help_outline

Specific form(s) of this reaction

More general form(s) of this reaction

RHEA:63694 a beta-D-glucuronoside + UDP + H(+) => alcohol glucuronate acceptor + UDP-alpha-D-glucuronate Reaction with net flow from right to left. ^help_outline

Related reactions ^help_outline