Rhea - reaction knowledgebase

UniProtKB ^help_outline	378,447 proteins
Enzyme classes ^help_outline	EC 2.7.7.7 DNA-directed DNA polymerase EC 2.7.7.31 DNA nucleotidylexotransferase EC 2.7.7.49 RNA-directed DNA polymerase
GO Molecular Function ^help_outline	GO:0034061 DNA polymerase activity

Reaction participants Show >> << Hide

Name ^help_outline DNA 5'-phosphate polymer Identifier CHEBI:173112 Charge -1 Formula (C5H7O5PR)n.H2O Search links Involved in 2 reaction(s) Find proteins in UniProtKB for this molecule Form(s) in this reaction:
- Identifier: RHEA-COMP:17339
  
  Polymer name: DNA_(n)
  
  Polymerization index ^help_outline n
  
  Formula H2O(C5H7O5PR)_n
  
  Charge (0)(-1)_n
  Mol File for the polymer
- Identifier: RHEA-COMP:17340
  
  Polymer name: DNA_(n+1)
  
  Polymerization index ^help_outline n+1
  
  Formula H2O(C5H7O5PR)_n+1
  
  Charge (0)(-1)_n+1
  Mol File for the polymer
Name ^help_outline a 2'-deoxyribonucleoside 5'-triphosphate Identifier CHEBI:61560 Charge -4 Formula C5H8O12P3R SMILES^help_outline [C@H]1([C@H](C[C@@H](O1)*)O)COP(OP(OP(=O)([O-])[O-])(=O)[O-])(=O)[O-] 2D coordinates Mol file for the small molecule Search links Involved in 79 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline diphosphate Identifier CHEBI:33019 (Beilstein: 185088) ^help_outline Charge -3 Formula HO7P2 InChIKey^help_outline XPPKVPWEQAFLFU-UHFFFAOYSA-K SMILES^help_outline OP([O-])(=O)OP([O-])([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 1,146 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule

	RHEA:22508	RHEA:22509	RHEA:22510	RHEA:22511
Reaction direction	undefined	left-to-right	right-to-left	bidirectional
UniProtKB ^help_outline	378,447 proteins	2,879 proteins	1 proteins
EC numbers ^help_outline	2.7.7.7 2.7.7.31 2.7.7.49
Gene Ontology ^help_outline	GO:0034061
KEGG ^help_outline				R00379
MetaCyc ^help_outline	DNA-NUCLEOTIDYLEXOTRANSFERASE-RXN	DNA-DIRECTED-DNA-POLYMERASE-RXN
EcoCyc ^help_outline	DNA-NUCLEOTIDYLEXOTRANSFERASE-RXN	DNA-DIRECTED-DNA-POLYMERASE-RXN

RNA-dependent DNA polymerase in virions of Rous sarcoma virus.

Temin H.M., Mizutani S.

Nature 226:1211-1213(1970) [PubMed] [EuropePMC]
RNA-dependent DNA polymerase in virions of RNA tumour viruses.

Baltimore D.

Nature 226:1209-1211(1970) [PubMed] [EuropePMC]
Enzymatic synthesis of deoxyribonucleic acid. I. Preparation of substrates and partial purification of an enzyme from Escherichia coli.

LEHMAN I.R., BESSMAN M.J., SIMMS E.S., KORNBERG A.

J Biol Chem 233:163-170(1958) [PubMed] [EuropePMC]
The terminal nucleotidyltransferases of calf thymus nuclei.

Gottesman M.E., Canellakis E.S.

J Biol Chem 241:4339-4352(1966) [PubMed] [EuropePMC]

This publication is cited by 1 other entry.
Biochemical studies of bacterial sporulation. II. Deoxy- ribonucleic acid polymerase in spores of Bacillus subtilis.

Falaschi A., Kornberg A.

J Biol Chem 241:1478-1482(1966) [PubMed] [EuropePMC]
Studies on the incorporation of deoxyribonucleic acid.

KRAKOW J.S., COUTSOGEORGOPOULOS C., CANELLAKIS E.S.

Biochim Biophys Acta 55:639-650(1962) [PubMed] [EuropePMC]

This publication is cited by 1 other entry.