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- Name help_outline chrodrimanin A Identifier CHEBI:156418 Charge 0 Formula C25H30O7 InChIKeyhelp_outline KCLJXKIILUZVBN-WREWNJFMSA-N SMILEShelp_outline C12=C3C(=CC(=C2C(O[C@@H]([C@@H]1O)C)=O)O)O[C@@]4([C@]([C@]5(C=CC(C([C@@]5(C[C@@H]4O)[H])(C)C)=O)C)(C3)[H])C 2D coordinates Mol file for the small molecule Search links Involved in 3 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline acetyl-CoA Identifier CHEBI:57288 (Beilstein: 8468140) help_outline Charge -4 Formula C23H34N7O17P3S InChIKeyhelp_outline ZSLZBFCDCINBPY-ZSJPKINUSA-J SMILEShelp_outline CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])([O-])=O)n1cnc2c(N)ncnc12 2D coordinates Mol file for the small molecule Search links Involved in 361 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline chrodrimanin B Identifier CHEBI:156420 Charge 0 Formula C27H32O8 InChIKeyhelp_outline DYQKBALSPZQWQD-FWEFFTEASA-N SMILEShelp_outline C12=C3C(=CC(=C2C(O[C@@H]([C@@H]1OC(C)=O)C)=O)O)O[C@@]4([C@]([C@]5(C=CC(C([C@@]5(C[C@@H]4O)[H])(C)C)=O)C)(C3)[H])C 2D coordinates Mol file for the small molecule Search links Involved in 1 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline CoA Identifier CHEBI:57287 (Beilstein: 11604429) help_outline Charge -4 Formula C21H32N7O16P3S InChIKeyhelp_outline RGJOEKWQDUBAIZ-IBOSZNHHSA-J SMILEShelp_outline CC(C)(COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])([O-])=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCS 2D coordinates Mol file for the small molecule Search links Involved in 1,511 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Cross-references
| RHEA:65324 | RHEA:65325 | RHEA:65326 | RHEA:65327 | |
|---|---|---|---|---|
| Reaction direction help_outline | undefined | left-to-right | right-to-left | bidirectional |
| UniProtKB help_outline |
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Publications
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Elucidation and heterologous reconstitution of chrodrimanin B biosynthesis.
Bai T., Quan Z., Zhai R., Awakawa T., Matsuda Y., Abe I.
The biosynthetic gene cluster of the fungal meroterpenoid chrodrimanin B (4) was discovered in Penicillium verruculosum TPU1311, and the complete biosynthetic pathway of 4 has been elucidated by heterologous reconstitution of its biosynthesis in Aspergillus oryzae, as well as by in vitro character ... >> More
The biosynthetic gene cluster of the fungal meroterpenoid chrodrimanin B (4) was discovered in Penicillium verruculosum TPU1311, and the complete biosynthetic pathway of 4 has been elucidated by heterologous reconstitution of its biosynthesis in Aspergillus oryzae, as well as by in vitro characterizations of selected enzymes. The present study has identified the polyketide synthase that produces 6-hydroxymellein (3) and also provided a biosynthetic platform of chrodrimanins for further bioengineering. << Less
Org. Lett. 20:7504-7508(2018) [PubMed] [EuropePMC]
This publication is cited by 14 other entries.