Reaction participants Show >> << Hide
- Name help_outline verruculide C epoxide Identifier CHEBI:156410 Charge 0 Formula C25H34O5 InChIKeyhelp_outline XTABYFFFAONWLS-YDIHSEQDSA-N SMILEShelp_outline C12=C(C(=CC(=C2C(O[C@@H](C1)C)=O)O)O)C/C=C(\C)/CC/C=C(\C)/CC[C@H]3C(C)(C)O3 2D coordinates Mol file for the small molecule Search links Involved in 2 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline 3-hydroxypentacecilide A Identifier CHEBI:156411 Charge 0 Formula C25H34O5 InChIKeyhelp_outline LUDRFZYCQUZPEW-VAVZLDKJSA-N SMILEShelp_outline C12=C3C(=CC(=C2C(O[C@@H](C1)C)=O)O)O[C@@]4([C@]([C@]5(CC[C@@H](C([C@@]5(CC4)[H])(C)C)O)C)(C3)[H])C 2D coordinates Mol file for the small molecule Search links Involved in 3 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Cross-references
| RHEA:65260 | RHEA:65261 | RHEA:65262 | RHEA:65263 | |
|---|---|---|---|---|
| Reaction direction help_outline | undefined | left-to-right | right-to-left | bidirectional |
| UniProtKB help_outline |
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Publications
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Elucidation and heterologous reconstitution of chrodrimanin B biosynthesis.
Bai T., Quan Z., Zhai R., Awakawa T., Matsuda Y., Abe I.
The biosynthetic gene cluster of the fungal meroterpenoid chrodrimanin B (4) was discovered in Penicillium verruculosum TPU1311, and the complete biosynthetic pathway of 4 has been elucidated by heterologous reconstitution of its biosynthesis in Aspergillus oryzae, as well as by in vitro character ... >> More
The biosynthetic gene cluster of the fungal meroterpenoid chrodrimanin B (4) was discovered in Penicillium verruculosum TPU1311, and the complete biosynthetic pathway of 4 has been elucidated by heterologous reconstitution of its biosynthesis in Aspergillus oryzae, as well as by in vitro characterizations of selected enzymes. The present study has identified the polyketide synthase that produces 6-hydroxymellein (3) and also provided a biosynthetic platform of chrodrimanins for further bioengineering. << Less
Org. Lett. 20:7504-7508(2018) [PubMed] [EuropePMC]
This publication is cited by 14 other entries.