Enzymes
| UniProtKB help_outline | 1 proteins |
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- Name help_outline (2E,6E)-farnesyl diphosphate Identifier CHEBI:175763 Charge -3 Formula C15H25O7P2 InChIKeyhelp_outline VWFJDQUYCIWHTN-YFVJMOTDSA-K SMILEShelp_outline CC(C)=CCC\C(C)=C\CC\C(C)=C\COP([O-])(=O)OP([O-])([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 177 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline H2O Identifier CHEBI:15377 (CAS: 7732-18-5) help_outline Charge 0 Formula H2O InChIKeyhelp_outline XLYOFNOQVPJJNP-UHFFFAOYSA-N SMILEShelp_outline [H]O[H] 2D coordinates Mol file for the small molecule Search links Involved in 6,264 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline 10-epi-cubebol Identifier CHEBI:138045 Charge 0 Formula C15H26O InChIKeyhelp_outline KONGRWVLXLWGDV-RODWMJHOSA-N SMILEShelp_outline C1C[C@H]([C@]2([C@]3([C@H]1C)CC[C@@]([C@]23[H])(O)C)[H])C(C)C 2D coordinates Mol file for the small molecule Search links Involved in 1 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
- Name help_outline diphosphate Identifier CHEBI:33019 (Beilstein: 185088) help_outline Charge -3 Formula HO7P2 InChIKeyhelp_outline XPPKVPWEQAFLFU-UHFFFAOYSA-K SMILEShelp_outline OP([O-])(=O)OP([O-])([O-])=O 2D coordinates Mol file for the small molecule Search links Involved in 1,139 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Cross-references
| RHEA:54064 | RHEA:54065 | RHEA:54066 | RHEA:54067 | |
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| Reaction direction help_outline | undefined | left-to-right | right-to-left | bidirectional |
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Publications
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A single terpene synthase is responsible for a wide variety of sesquiterpenes in Sorangium cellulosum Soce56.
Schifrin A., Khatri Y., Kirsch P., Thiel V., Schulz S., Bernhardt R.
The myxobacterium Sorangium cellulosum So ce56 is a prolific producer of volatile sesquiterpenes. The strain harbours one of the largest prokaryotic genomes (13.1 Mbp). However, it codes only for three type I terpene synthases (TSs; sce1440, sce6369, sce8552) and one type II TS (sce4636), responsi ... >> More
The myxobacterium Sorangium cellulosum So ce56 is a prolific producer of volatile sesquiterpenes. The strain harbours one of the largest prokaryotic genomes (13.1 Mbp). However, it codes only for three type I terpene synthases (TSs; sce1440, sce6369, sce8552) and one type II TS (sce4636), responsible for the production of at least 17 sesquiterpenes. We report here the gene expression of TSs and biosynthesis of the TS products in E. coli. Comparison with the So ce56 volatiles allows the assignment of the terpenes to their synthesizing genes. Both, the geosmin synthase sce1440 and the previously examined (+)-eremophilene synthase sce8552 are highly specific. In contrast, Sce6369, the first characterized 10-epi-cubebol synthase, is responsible for the formation of most of the So ce56 sesquiterpenes, mainly cadalanes and cubebanes. In contrast, Sce4636 does not convert FPP. Having characterized the So ce56 TSs, we screened all the 27 sequenced myxobacterial species from the NCBI and JGI-IMG databases for parent genes to predict the sesquiterpenes produced by them. << Less