Reaction participants Show >> << Hide
- Name help_outline (S)-dihydroorotate Identifier CHEBI:30864 Charge -1 Formula C5H5N2O4 InChIKeyhelp_outline UFIVEPVSAGBUSI-REOHCLBHSA-M SMILEShelp_outline [O-]C(=O)[C@@H]1CC(=O)NC(=O)N1 2D coordinates Mol file for the small molecule Search links Involved in 10 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
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Name help_outline
a menaquinone
Identifier
CHEBI:16374
(CAS: 11032-49-8)
help_outline
Charge
0
Formula
(C5H8)nC11H8O2
Search links
Involved in 47 reaction(s)
Find proteins in UniProtKB for this molecule
Form(s) in this reaction:
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Identifier: RHEA-COMP:9537Polymer name: a menaquinonePolymerization index help_outline nFormula C11H8O2(C5H8)nCharge (0)(0)nMol File for the polymer
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Name help_outline
a menaquinol
Identifier
CHEBI:18151
Charge
0
Formula
C11H10O2(C5H8)n
Search links
Involved in 53 reaction(s)
Find proteins in UniProtKB for this molecule
Form(s) in this reaction:
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Identifier: RHEA-COMP:9539Polymer name: a menaquinolPolymerization index help_outline nFormula C11H10O2(C5H8)nCharge (0)(0)nMol File for the polymer
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- Name help_outline orotate Identifier CHEBI:30839 (Beilstein: 3651747; CAS: 73-97-2) help_outline Charge -1 Formula C5H3N2O4 InChIKeyhelp_outline PXQPEWDEAKTCGB-UHFFFAOYSA-M SMILEShelp_outline [O-]C(=O)c1cc(=O)[nH]c(=O)[nH]1 2D coordinates Mol file for the small molecule Search links Involved in 14 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Cross-references
| RHEA:29195 | RHEA:29196 | RHEA:29197 | RHEA:29198 | |
|---|---|---|---|---|
| Reaction direction help_outline | undefined | left-to-right | right-to-left | bidirectional |
| UniProtKB help_outline |
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Related reactions help_outline
Specific form(s) of this reaction
More general form(s) of this reaction
Publications
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Dihydroorotate dehydrogenase (Escherichia coli).
Karibian D.
Methods Enzymol 51:58-63(1978) [PubMed] [EuropePMC]
This publication is cited by 1 other entry.
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The anaerobic oxidation of dihydroorotate by Escherichia coli K-12.
Andrews S., Cox G.B., Gibson F.
The oxidation of dihydroorotate under anaerobic conditions has been examined using various mutant strains of Escherichia coli K-12. This oxidation in cells grown anaerobically in a glucose minimal medium is linked via menaquinone to the fumarate reductase enzyme coded for by the frd gene and is in ... >> More
The oxidation of dihydroorotate under anaerobic conditions has been examined using various mutant strains of Escherichia coli K-12. This oxidation in cells grown anaerobically in a glucose minimal medium is linked via menaquinone to the fumarate reductase enzyme coded for by the frd gene and is independent of the cytochromes. The same dihydroorotate dehydrogenase protein functions in both the anaerobic and aerobic oxidation of dihydroorotate. Ferricyanide can act as an artificial electron acceptor for dihydroorotate dehydrogenase and the dihydroorotate-menaquinone-ferricyanide reductase activity can be solubilised by 2 M guanidine-HCl with little loss of activity. << Less
Biochim Biophys Acta 462:153-160(1977) [PubMed] [EuropePMC]
This publication is cited by 1 other entry.