Rhea - reaction knowledgebase

Enzyme class ^help_outline	EC 1.13.11.17 indole 2,3-dioxygenase
GO Molecular Function ^help_outline	GO:0047719 indole 2,3-dioxygenase activity

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Name ^help_outline indole Identifier CHEBI:16881 (Beilstein: 107693; CAS: 120-72-9) ^help_outline Charge 0 Formula C8H7N InChIKey^help_outline SIKJAQJRHWYJAI-UHFFFAOYSA-N SMILES^help_outline c1cc2ccccc2[nH]1 2D coordinates Mol file for the small molecule Search links Involved in 9 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline O₂ Identifier CHEBI:15379 (CAS: 7782-44-7) ^help_outline Charge 0 Formula O2 InChIKey^help_outline MYMOFIZGZYHOMD-UHFFFAOYSA-N SMILES^help_outline O=O 2D coordinates Mol file for the small molecule Search links Involved in 2,779 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule
Name ^help_outline 2-formamidobenzaldehyde Identifier CHEBI:18033 Charge 0 Formula C8H7NO2 InChIKey^help_outline PVIMSPYDDGDCTG-UHFFFAOYSA-N SMILES^help_outline [H]C(=O)Nc1ccccc1C([H])=O 2D coordinates Mol file for the small molecule Search links Involved in 1 reaction(s) Find molecules that contain or resemble this structure Find proteins in UniProtKB for this molecule

AN INDOLE OXIDASE ISOLATED FROM THE LEAVES OF TECOMA STANS.

NAIR P.M., VAIDYANATHAN C.S.

Biochim Biophys Acta 81:496-506(1964) [PubMed] [EuropePMC]
Purification and Characterization of a New Indole Oxygenase from the Leaves of Tecoma stans L.

Kunapuli S.P., Vaidyanathan C.S.

A new indole oxygenase from the leaves of Tecoma stans was isolated and purified to homogenity. The purified enzyme system catalyzes the conversion of indole to anthranilic acid. It is optimally active at pH 5.2 and 30 degrees C. Two moles of oxygen are consumed and one mole of anthranilic acid is ... >> More

A new indole oxygenase from the leaves of Tecoma stans was isolated and purified to homogenity. The purified enzyme system catalyzes the conversion of indole to anthranilic acid. It is optimally active at pH 5.2 and 30 degrees C. Two moles of oxygen are consumed and one mole of anthranilic acid is formed for every mole of indole oxidized. Dialysis resulted in complete loss of the activity. The inactive enzyme could be reactivated by the addition of concentrated dialysate. The enzyme is not inhibited by copper-specific chelators, non-heme iron chelators or atebrin. It is not a cuproflavoprotein, unlike the other indole oxygenases and oxidases. << Less

Plant Physiol 71:19-23(1983) [PubMed] [EuropePMC]
Detection of an indole oxidizing system in maize leaves.

Chauhan Y.S., Rathore V.S., Garg G.K., Bhargava A.

Biochem Biophys Res Commun 83:1237-1245(1978) [PubMed] [EuropePMC]